An evaluation of the total quality management implementation strategy for the advanced solid rocket motor project at NASA's Marshall Space Flight Center

An evaluation of the NASA's Marshall Space Flight Center (MSFC) strategy to implement Total Quality Management (TQM) in the Advanced Solid Rocket Motor (ASRM) Project is presented. The evaluation of the implementation strategy reflected the Civil Service personnel perspective at the project level. The external and internal environments at MSFC were analyzed for their effects on the ASRM TQM strategy. Organizational forms, cultures, management systems, problem solving techniques, and training were assessed for their influence on the implementation strategy. The influence of ASRM's effort was assessed relative to its impact on mature projects as well as future projects at MSFC

Emergency Wildlife Management Response to Protect Evidence Associated with the Terrorist Attack on the World Trade Center, New York City

At the request of the New York City Police Department, the PoIt Authority of New York and New Jersey, and the New York State Department of Environmental Conservation, a team of USDA APHIS Wildlife Services (WS) biologists mobilized in less than 24 hours to assist federal, state and local law enforcement officials in managing birds and rodents impacting the recovey of evidence as a result of the September 11, 2001 terrorist attacks on the World Trade Center. During the 10-month recovery effort fiom September 2001 to June 2002, more than 1.7 million tons of debris was shipped fiom Ground Zero in Manhatran to a high-security crime scene at the Fresh W s Landfill (FKL), Staten Island, New York Close to a billion pieces of debris were sorted by law enforcement officials to recover personal effects, human remains, and other evidence to document the crime and identlfy victims, as part of the largest forensic investigation in U.S. history. Within days of bringing debris to FKL, more than 2,600 gulls were on site, disrupting work of law enforcement officials and creating a concem that evidence would be lost to birds. Historically, FKL has been a feeding and loafmg site for over 100,000 gulls. To address this unprecedented wildlife damage management problem, WS implemented an integrated bud and rodent management program that involved 69 biologists from 23 states. The goal was to reduce the impact of pus, crows, house mice, and Norway rats on law enforcement personnel, equipment, and evidence collection including a zero-tolerance policy for gulls and crows landing on the working face. A combination of population surveys and direct management activities targeting gulls and crows was initiated 12-14 hours a day, 7 days a week using visual and noise deterrents including pyrotechnics, mylar tape, human and dead-bud effigies, lasers, paint ball guns, and lethal removal of a limited number of birds. In addition, commensal rodent surveys with snap traps were conducted twice monthly to document population trends and explore the need for rodent control on site. We deployed over 23,000 pyrotechnics and dispased over 172,000 gulls and 5,000 crows fiom the site. We removed 293 house mice and 46 Norway rats in 6,000 trapnights. \u27Ibe program was highly effective in preventing gulls and crows from feeding on remains and disrupting workers. We discuss other key lessons learned regarding an emergency response program to manage wildlife

Emergency Wildlife Management Response to Protect Evidence Associated with the Terrorist Attack on the World Trade Center, New York City

At the request of the New York City Police Department, the PoIt Authority of New York and New Jersey, and the New York State Department of Environmental Conservation, a team of USDA APHIS Wildlife Services (WS) biologists mobilized in less than 24 hours to assist federal, state and local law enforcement officials in managing birds and rodents impacting the recovey of evidence as a result of the September 11, 2001 terrorist attacks on the World Trade Center. During the 10-month recovery effort fiom September 2001 to June 2002, more than 1.7 million tons of debris was shipped fiom Ground Zero in Manhatran to a high-security crime scene at the Fresh W s Landfill (FKL), Staten Island, New York Close to a billion pieces of debris were sorted by law enforcement officials to recover personal effects, human remains, and other evidence to document the crime and identlfy victims, as part of the largest forensic investigation in U.S. history. Within days of bringing debris to FKL, more than 2,600 gulls were on site, disrupting work of law enforcement officials and creating a concem that evidence would be lost to birds. Historically, FKL has been a feeding and loafmg site for over 100,000 gulls. To address this unprecedented wildlife damage management problem, WS implemented an integrated bud and rodent management program that involved 69 biologists from 23 states. The goal was to reduce the impact of pus, crows, house mice, and Norway rats on law enforcement personnel, equipment, and evidence collection including a zero-tolerance policy for gulls and crows landing on the working face. A combination of population surveys and direct management activities targeting gulls and crows was initiated 12-14 hours a day, 7 days a week using visual and noise deterrents including pyrotechnics, mylar tape, human and dead-bud effigies, lasers, paint ball guns, and lethal removal of a limited number of birds. In addition, commensal rodent surveys with snap traps were conducted twice monthly to document population trends and explore the need for rodent control on site. We deployed over 23,000 pyrotechnics and dispased over 172,000 gulls and 5,000 crows fiom the site. We removed 293 house mice and 46 Norway rats in 6,000 trapnights. \u27Ibe program was highly effective in preventing gulls and crows from feeding on remains and disrupting workers. We discuss other key lessons learned regarding an emergency response program to manage wildlife

Emergency Wildlife Management Response to Protect Evidence Associated with the Terrorist Attack on the World Trade Center, New York City

At the request of the New York City Police Department, the PoIt Authority of New York and New Jersey, and the New York State Department of Environmental Conservation, a team of USDA APHIS Wildlife Services (WS) biologists mobilized in less than 24 hours to assist federal, state and local law enforcement officials in managing birds and rodents impacting the recovey of evidence as a result of the September 11, 2001 terrorist attacks on the World Trade Center. During the 10-month recovery effort fiom September 2001 to June 2002, more than 1.7 million tons of debris was shipped fiom Ground Zero in Manhatran to a high-security crime scene at the Fresh W s Landfill (FKL), Staten Island, New York Close to a billion pieces of debris were sorted by law enforcement officials to recover personal effects, human remains, and other evidence to document the crime and identlfy victims, as part of the largest forensic investigation in U.S. history. Within days of bringing debris to FKL, more than 2,600 gulls were on site, disrupting work of law enforcement officials and creating a concem that evidence would be lost to birds. Historically, FKL has been a feeding and loafmg site for over 100,000 gulls. To address this unprecedented wildlife damage management problem, WS implemented an integrated bud and rodent management program that involved 69 biologists from 23 states. The goal was to reduce the impact of pus, crows, house mice, and Norway rats on law enforcement personnel, equipment, and evidence collection including a zero-tolerance policy for gulls and crows landing on the working face. A combination of population surveys and direct management activities targeting gulls and crows was initiated 12-14 hours a day, 7 days a week using visual and noise deterrents including pyrotechnics, mylar tape, human and dead-bud effigies, lasers, paint ball guns, and lethal removal of a limited number of birds. In addition, commensal rodent surveys with snap traps were conducted twice monthly to document population trends and explore the need for rodent control on site. We deployed over 23,000 pyrotechnics and dispased over 172,000 gulls and 5,000 crows fiom the site. We removed 293 house mice and 46 Norway rats in 6,000 trapnights. \u27Ibe program was highly effective in preventing gulls and crows from feeding on remains and disrupting workers. We discuss other key lessons learned regarding an emergency response program to manage wildlife

Individual Response to Risk As a Function of Normative Social Pressure: A Pilot Study of Seat Belt Use

The authors attempt to clarify some of the variables that influence whether people act appropriately when a Risk is substantial and subject to individual control. They do so by reporting results of a pilot study of seat belt use. Also, the authors believe their approach to be generalizable to problems such as encouraging people to test for radon, to use condoms to prevent AIDS or to quit smoking

Larval abundance of summer flounder (Paralichthys dentatus) as a measure of recruitment and stock status

Summer flounder (Paralichthys dentatus) is one of the most economically and ecologically important estuarine-dependent species in the northeastern United States. The status of the population is currently a topic of controversy. Our goal was to assess the potential of using larval abundance at ingress as another fishery independent measure of spawning stock biomass or recruitment. Weekly long-term ichthyoplankton time series were analyzed from Little Egg Inlet, New Jersey (1989–2006) and Beaufort Inlet, North Carolina (1986–2004). Mean size-at-ingress and stage were similar between sites, whereas timing of ingress and abundance at ingress were not similar. Ingress primarily occurred during the fall at Little Egg Inlet and the winter at Beaufort Inlet. These findings agree with those from earlier studies in which at least two stocks (one north and one south of Cape Hatteras) were identified with different spawning periods. Larval abundance at Little Egg Inlet has increased since the late 1990s and most individuals now enter the estuary earlier during the season of ingress. Abundance at Little Egg Inlet was correlated with an increase in spawning stock biomass, presumably because spawning by larger, more abundant fish during the late 1990s and early 2000s provided increased larval supply, at least in some years. Larval abundance at ingress at Beaufort Inlet was not correlated with spawning stock biomass or with larval abundance at ingress at Little Egg Inlet, further supporting the hypothesis of at least two stocks. Larval abundance at Little Egg Inlet could be used as a fishery-independent index of spawning stock size north of Cape Hatteras in future stock assessments. Larval occurrence at Beaufort Inlet may provide information on the abundance of the stock south of Cape Hatteras, but additional stock assessment work is required

Clinical Features and Associated Likelihood of Primary Ciliary Dyskinesia in Children and Adolescents

Rationale: Primary ciliary dyskinesia (PCD), a genetically heterogeneous, recessive disorder of motile cilia, is associated with distinct clinical features. Diagnostic tests, including ultrastructural analysis of cilia, nasal nitric oxide measurements, and molecular testing for mutations in PCD genes, have inherent limitations

Joint contributions of rare copy number variants and common SNPs to risk for schizophrenia

Objective: Both rare copy number variants (CNVs) and common single-nucleotide polymorphisms (SNPs) contribute to liability to schizophrenia, but their etiological relationship has not been fully elucidated. The authors evaluated an additive model whereby risk of schizophrenia requires less contribution from common SNPs in the presence of a rare CNV, and tested for interactions. Method: Genetic data from 21,094 case subjects with schizophrenia and 20,227 control subjects from the Psychiatric Genomics Consortium were examined. Three classes of rare CNVs were assessed: CNVs previously associated with schizophrenia, CNVs with large deletions ≥500 kb, and total CNV burden. The mean polygenic risk scores (PRSs) between study subjects with and without rare CNVs were compared, and joint effects of PRS and CNVs on schizophrenia liability were modeled by using logistic regression. Results: Schizophrenia case subjects carrying risk CNVs had a lower polygenic risk than case subjects without risk CNVs but a higher risk than control subjects. For case subjects carrying known risk CNVs, the PRS was diminished in proportion to the effect size of the CNV. The strongly associated 22q11.2 deletion required little added PRS to produce schizophrenia. Large deletions and increased CNV burden were also associated with lower polygenic risk in schizophrenia case subjects but not in control subjects or after removal of known risk CNV carriers. Conclusions: The authors found evidence for interactive effects of PRS and previously associated CNVs for risk for schizophrenia, and the results for large deletions and total CNV burden support an additive model. These findings offer insights into the genetic architecture of schizophrenia by illuminating how different established genetic risk factors act and interact to influence liability to schizophrenia